Ingredients & studies

Aloe Vera

wound healing // collagen production // antioxidant // antibacterial

• Pharmacological Update Properties of Aloe Vera and its Major Active Constituents

• The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review

• Ozonated Aloe vera Oil Effective Increased the Number of Fibroblasts and Collagen Thickening in the Healing Response of Full-Thickness Skin Defects

amla oil

anti-inflammatory // vitamin rich // wound healing // antioxidant

• Phytochemistry, pharmacology and medicinal properties of Phyllanthus emblica Linn

• Emblica officinalis and hepatocarcinogenesis: a chemopreventive study in Wistar rats

• Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms

• Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder

• Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer

Argan Oil

wound healing // burn treatment // cardioprotective properties

• Physicochemical characteristics, nutritional properties, and health benefits of argan oil: a review

• Therapeutic potential of argan oil: a review

• Hypolipidemic and hypocholesterolemic effect of argan oil (Argania spinosa L.) in Meriones shawi rats

• The Effects of Argan Oil in Second-degree Burn Wound Healing in Rats

• Activation of MITF by Argan Oil Leads to the Inhibition of the Tyrosinase and Dopachrome Tautomerase Expressions in B16 Murine Melanoma Cells

ASTAXANTHIN

antioxidant // immunoenhancing // anti-inflammatory

• Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review

• Astaxanthin: a review of its chemistry and applications

• Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae

• Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects

• Antioxidant properties evaluation of topical astaxanthin formulations as anti-aging products

Avocado

hair growth // collagen production // wound healing // antioxidant

• Protective Mechanisms of Avocado Oil Extract Against Ototoxicity

• Avocado Oil: Characteristics, Properties, and Applications

• The effect of various avocado oils on skin collagen metabolism

• Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils

• Consumption of avocado oil (Persea americana) improves the biochemical profile of rats submitted to long-term androgenic stimulation

• Avocado Oil Extract Modulates Auditory Hair Cell Function through the Regulation of Amino Acid Biosynthesis Genes

bamboo

hair growth // anti-inflammatory // dietary supplement

• Quantitative assessment of silicon in fresh and processed bamboo shoots and its potential as functional element in food, nutraceuticals and cosmeceuticals

• Quantifying Tensile Properties of Bamboo Silicone Biocomposite using Yeoh Model

• Bamboo Extract for Hair Growth: Research and Studies

• Bamboo vinegar decreases inflammatory mediator expression and NLRP3 inflammasome activation by inhibiting reactive oxygen species generation and protein kinase C-α/δ activation

• Extract of Bambusae Caulis in Taeniam inhibits cigarette smoke-induced pulmonary and intestinal inflammation

birch organic sap

wound healing // tissue regeneration

• From a Traditional Medicinal Plant to a Rational Drug: Understanding the Clinically Proven Wound Healing Efficacy of Birch Bark Extract

• Betulinic acid triggers apoptosis and inhibits migration and invasion of gastric cancer cells by impairing EMT progress

• Topical treatment of necrotising herpes zoster with betulin from birch bark

• The Natural Product Betulinic Acid Rapidly Promotes Amyloid-β Fibril Formation at the Expense of Soluble Oligomers

• Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)

• Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cells

• Betulinic acid induces apoptosis and impairs migration and invasion in a mouse model of ovarian cancer

• The Wound Healing Properties of Betulin from Birch Bark from Bench to Bedside

Bringraj Oil

hair growth // vitamin rich // analgesic

• Eclipta alba extract with potential for hair growth promoting activity

• Wonder herb bhringraj - how to use bhringraj oil for hair growth

• Phytochemistry and neuroprotective effects of Eclipta alba (L.) Hassk

• Analgesic studies on total alkaloids and alcohol extracts of Eclipta alba (Linn.) Hassk

• What You Need to Know About the Health Benefits of Bhringraj Oil

• Hair growth promoting activity of Eclipta alba in male albino rats

calendula

wound healing // anti-inflammatory

• Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action

• A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation

• A systematic review of Calendula officinalis extract for wound healing

• Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent

• Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer

camellia

anti-inflammatory // wound healing // scar reduction // antioxidant

• Anti-inflammatory and antioxidative effects of Camellia oleifera Abel components

• Beneficial effects of Camellia Oil (Camellia oleifera Abel.) on ketoprofen-induced gastrointestinal mucosal damage through upregulation of HO-1 and VEGF

• Potential Bioactive Components and Health Promotional Benefits of Tea ( Camellia sinensis)

• Benefits & Uses Of Camellia Oil (Tea Seed Oil)

• The Effect of Camellia sinensis on Wound Healing Potential in an Animal Model

Cistus Incanus

anti-bacterial // anti-viral // anti-inflammatory // antioxidant

• Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study

• Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins

• Results of a randomized controlled phase III trial: efficacy of polyphenol-containing cystus® tea mouthwash solution for the reduction of mucositis in head and neck cancer patients undergoing external beam radiotherapy

• Cistus: A Natural Antibiotic, Antiviral And Biofilm Buster

• Cistus incanus from Strandja Mountain as a Source of Bioactive Antioxidants

• Cistus incanus a promising herbal tea rich in bioactive compounds: LC–MS/MS determination of catechins, flavonols, phenolic acids and alkaloids—A comparison with Camellia sinensis, Rooibos and Hoan Ngoc herbal tea

comfrey oil

anti-inflammatory // joint health // antioxidant // wound healing

• Comfrey root: from tradition to modern clinical trials

• Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study

• Proliferative and antioxidant activity of Symphytum officinale root extract

• Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study

• A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-κB Signaling

flaxseed oil

cardioprotective properties // anti-inflammatory

• Flaxseed: its bioactive components and their cardiovascular benefits

• Flaxseed and Flaxseed Oil

• Flaxseed for Health and Disease: Review of Clinical Trials

• Dietary Flaxseed as a Strategy for Improving Human Health

green coffee oil

antioxidant // instestine stabilizer // anti-inflammatory

• An apple plus a Brazil nut a day keeps the doctors away: antioxidant capacity of foods and their health benefits

• Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa

• Coffea arabica extract and its constituents prevent photoaging by suppressing MMPs expression and MAP kinase pathway

• Antioxidant activity of the aqueous and methanolic extracts of coffee beans (Coffea arabica L.)

• Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee ( Coffea arabica L.) Bean Residual Press Cake on the Skin Wound Healing

Helichrysum Italicum

cell proliferation // scar reduction // wound healing // anti-inflammatory

• Helichrysum italicum: From traditional use to scientific data

• Effects of Helichrysum italicum extract on growth and enzymatic activity of Staphylococcus aureusPub. 2001

• In Vitro Anticollagenase and Antielastase Activities of Essential Oil of Helichrysum italicum subsp. italicum (Roth) G. Don

• Biological properties and resistance reversal effect of Helichrysum italicum (Roth) G. Don Pub. 2019

• Identification and quantitative determination of the polar constituents in Helichrysum italicum flowers and derived food supplements

• The Differences Between Helichrysum Essential Oils - Aromatherapy, Botanical Profiles, Reference Guides

Hyaluronic Acid

moisturizer // wound healing // tissue hydration // analgesic

• Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory

• Hyaluronic Acid in Inflammation and Tissue Regeneration

• Physiochemical properties and application of hyaluronic acid: a systematic review

• Efficacy and safety of repeated courses of hyaluronic acid injections for knee osteoarthritis: A systematic review

• Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects

• The efficacy of multiple versus single hyaluronic acid injections: a systematic review and meta-analysis

lavender

wound healing // sleep aid // collagen expression

• Wound healing potential of lavender oil by acceleration of granulation and wound contraction through induction of TGF-β in a rat model

• Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance

• Effect of Inhalation of Lavender Essential Oil on Vital Signs in Open Heart Surgery ICU

• Effect of lavender aromatherapy on vital signs and perceived quality of sleep in the intermediate care unit: a pilot study

• The Effects of Lavender Essential Oil on Wound Healing: A Review of the Current Evidence

manuka honey

antimicrobial // antioxidant // wound healing // tissue regeneration // anti-inflammatory

• The Composition and Biological Activity of Honey: A Focus on Manuka Honey

• Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration

• Antibacterial activity of Manuka honey and its components: An overview

• Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats

• Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats

• The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle

medium-chain triglyceride (MCT) oil

anti-inflammatory // wound healing

• Influence of the Oil Phase and Topical Formulation on the Wound Healing Ability of a Birch Bark Dry Extract

• Microcurrent skin patches for postoperative pain control in total knee arthroplasty: a pilot study

• Medium Chain Triglyceride (MCT) Oil Affects the Immunophenotype via Reprogramming of Mitochondrial Respiration in Murine Macrophages

• The Use of Medium-Chain Triglycerides in Gastrointestinal Disorders

Methylsulfonylmethane (MSM)

wound healing // collagen production // analgesic

• Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement

• Suppressive effect of methylsulfonylmethane (MSM) on type II collagen-induced arthritis in DBA/1J mice

• Methylsulfonylmethane (MSM) Treatment Enhances C2C12 Wound Closure and Protects Cells from Oxidative Stress

• Topically Applied Metal Chelator Reduces Thermal Injury Progression in a Rat Model of Brass Comb Burn

rosemary

wound healing // anti-inflammatory // collagen production

• Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols

• Healing potential of Rosmarinus officinalis L. on full-thickness excision cutaneous wounds in alloxan-induced-diabetic BALB/c mice

• Accelerated infected wound healing by topical application of encapsulated Rosemary essential oil into nanostructured lipid carriers

• Anti-inflammatory and antinociceptive effects of Rosmarinus officinalis L. essential oil in experimental animal models

• Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain

sapote oil

antioxidant // vitamin rich // scalp health

• Mamey sapote fruit and carotenoid formulations derived thereof are dietary sources of vitamin A - A comparative randomized cross-over study

• Effective anti-cancer property of Pouteria sapota leaf on breast cancer cell lines

• Antioxidant activity, ascorbic acid and total phenol of exotic fruits occurring in Brazil

• Mamey Sapote Oil

sea buckthorn oil

wound healing // immuno-enhancing // anti-inflammatory

• A preclinical study of the effects of seabuckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats

• Healing effect of sea buckthorn, olive oil, and their mixture on full-thickness burn wounds

• Healing efficacy of sea buckthorn (Hippophae rhamnoides L.) seed oil in an ovine burn wound model

• The Anticancer Activity of Sea Buckthorn [Elaeagnus rhamnoides (L.) A. Nelson]

• Leaves of Hippophae rhamnoides prevent taste aversion in gamma-irradiated rats

• Protective effects of seabuckthorn pulp and seed oils against radiation-induced acute intestinal injury

• UV radiation-induced skin aging in hairless mice is effectively prevented by oral intake of sea buckthorn (Hippophae rhamnoides L.) fruit blend for 6 weeks through MMP suppression and increase of SOD activity

• Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial

• Immunoprotective Effect of Seabuckthorn (Hippophae rhamnoides) and Glucomannan on T-2 Toxin-Induced Immunodepression in Poultry

st. john’s wort

antibacterial // anti-inflammatory

• Topical application of St. John's wort (Hypericum perforatum)

• The effect of Hypericum perforatum on the wound healing and scar of cesarean

• A review of the antibacterial activity of Hypericum perforatum L

• Endemic North American Plants as Potentially Suitable Agents for Wound Cleaning Under Resource Scarce Conditions

sunflower oil

cell regeneration // anti-inflammatory

• Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care

• The benefits of sunflower oleodistillate (SOD) in pediatric dermatology

• Topically applied sunflower seed oil prevents invasive bacterial infections in preterm infants in Egypt: a randomized, controlled clinical trial

• Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils

• Impact of sunflower seed oil versus mustard seed oil on skin barrier function in newborns: a community-based, cluster-randomized trial

vegetable glycerin

humectant // wound healing

• The Benefits of Glycerin in Skin Care

• Glycerin-Based Hydrogel for Infection Control

• A Preliminary Study on the Effectiveness of Glycerin Magnesia Dressing on Second Intension Healing of Wounds on the Distal Aspect of the Forelimb of Horses

• Therapeutic glycerin-based ointment provides healing benefits

white willow bark

analgesic // anti-inflammatory // wound healing

• Anti-inflammatory effects of the willow bark extract STW 33-I (Proaktiv(®)) in LPS-activated human monocytes and differentiated macrophages

• Efficacy and Safety of White Willow Bark (Salix alba) Extracts

• Herbal medicine for low-back pain

• A systematic review on the effectiveness of willow bark for musculoskeletal pain

• Willow species and aspirin: different mechanism of actions

• Willow Bark: Nature’s Aspirin